Two people have been airlifted to hospital and several horses have been killed in a crash in the NSW Hunter Region

NSW Police said the crash happened about 6.30am this morning near Muswellbrook after the livestock truck ran into a tree.

The “serious crash” had closed the Golden Highway at Jerrys Plains, near Singleton and 200km north of Sydney.

The scene at Golden Highway, Jerrys Plains. (Mangoola Rural Fire Brigade NSW)

A NSW Police spokeswoman said they were still establishing the details of the accident, amid reports the five animals killed were prized racehorses.

The driver, a 62-year-old man, and a 59-year-old male passenger were treated at the scene by paramedics, before being airlifted to John Hunter Hospital in a serious condition.

Their injuries are not believed to be life-threatening.

All five of the horses that were being transported in the vehicle died as a result of the collision.

This content first appear on 9news

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